I have Pi Hole installed on my combined front and backend media server in order to reduce the amount of adverts I see to great effect.
I've listed here the reasons I love using Pi Hole.
1) YouTube clients
My TV has a Youtube client installed which gets a lot of use in my house. The way they play adverts is most times a new video is chosen, and also DURING a long video. Pi Hole makes the Youtube app act as though adverts don't exist. The videos never pause, I don't get the slightest of delays when launching a video. Long may that continue!
2) Web browsing
This is probably the most common use of Pi-Hole and simply put, it's astonishing how much of your traffic is adverts. Furthermore, some pages are unusable to me caked in adverts. Step in Pi Hole. It's a sad state of affairs but using this technology is the only way I can make such sites accessible.
3) Mobile apps (especially kids games)
One of the best outcomes of having no adverts has been with my young (toddler) child playing games on my Android phone. I don't know if you've ever played a low quality free game from the Play Store, but a LOT of games lately seem to have a two pronged approach to getting money. One is In App Purchases which are often big shiny attractive buttons which a toddler is likely to gravitate towards. (The ethics behind earning revenue from tactics like these is akin to a con man in my opinion.)
The second way these games are monitised is the use of constant, intrusive and often colourful bright banner adverts. It's sometimes difficult even as a phone literate guy with good eyesight to figure out how to close full screen adverts to get back to the game, they're that intrusive. Pi-Hole blocks these adverts, making cheap, poor quality games slightly more bearable.
I'm a huge fan of this software. You can chat about it with a friendly bunch at Reddit